CRC Research Update — July 06, 2026
Today's colorectal cancer research highlights
liver-mets
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CRC Research Finding
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Dihydroartemisinin targets KRASG12D to overcome immunotherapy resistance
Anti-malaria drug selectively downregulates KRASG12D mutant protein and enhances regorafenib plus anti-PD-1 in preclinical liver metastasis models. (Cell Death & Disease)
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CRC Research Update — July 02, 2026
Today's colorectal cancer research highlights
KRAS Mutations Predict Worse Outcomes After Liver Metastasis Surgery
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The CRC Digest
KRAS Mutations Predict Worse Outcomes After Liver Metastasis Surgery
In 190 patients who had curative liver surgery for colorectal metastases, KRAS mutations (37.9% of patients) were associated with significantly worse overall and recurrence-free survival and more aggressive recurrence patterns. (Surgery Today)
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CRC Research Update — July 01, 2026
Today's colorectal cancer research highlights
French multicenter study to evaluate ctDNA after liver metastasis surgery
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French multicenter study to evaluate ctDNA after liver metastasis surgery
The CLIMES PRODIGE 77 study will enroll 232 patients undergoing curative-intent liver metastasis resection to evaluate circulating tumor DNA as a biomarker for detecting minimal residual disease and predicting prognosis. (BMJ Open)
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CRC Research Finding
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▸ Multi-omics deep learning model predicts anti-EGFR therapy response in liver metastases
A multi-center study developed a deep learning framework integrating multi-omics data to predict which RAS wild-type colorectal cancer liver metastases patients will benefit from cetuximab therapy, addressing primary resistance challenges. (Curr Cancer Drug
CRC Research Update — June 30, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 26, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 25, 2026
Today's colorectal cancer research highlights