BREAKWATER explores molecular markers in BRAF V600E disease Skip to content The CRC Digest BREAKWATER explores molecular markers in BRAF V600E disease Phase III trial data from ESMO GI examines correlates of response to encorafenib plus cetuximab and chemo. (Oncodaily) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team.
BRAF V600E screening identifies candidates for perioperative therapy Skip to content The CRC Digest BRAF V600E screening identifies candidates for perioperative therapy Multicenter screening evaluated preoperative BRAF V600E mutation detection in patients with resectable colorectal oligometastases, enabling recruitment to a trial of the BEACON triplet regimen. (Int J Clin Oncol) This content is informational only and does not
BRAF V600E triplet regimen advances in phase 3 trial Skip to content The CRC Digest BRAF V600E triplet regimen advances in phase 3 trial BREAKWATER Cohort 3 evaluated encorafenib + cetuximab + FOLFIRI versus FOLFIRI ± bevacizumab in previously untreated BRAF V600E-mutant mCRC, with primary endpoint of objective response rate and key secondary endpoint of progression-free survival. (Annals of Oncology) This content