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crc-research

A collection of 699 issues

Pre-chemotherapy anxiety and sleep disturbance linked to immune changes and quality of life

Skip to content The CRC Digest ♥ LIVING WITH CRC Pre-chemotherapy anxiety and sleep disturbance linked to immune changes and quality of life A prospective study of 268 CRC patients assessed within 24 hours before their first chemotherapy cycle found that anxiety-sleep disturbance symptoms were associated with neuroendocrine dysregulation, cellular immune

Smartphone-based education program for family caregivers of CRC patients

Skip to content The CRC Digest ♥ LIVING WITH CRC Smartphone-based education program for family caregivers of CRC patients A randomized controlled trial of 80 family caregivers of CRC patients tested a smartphone-based educational program designed to meet supportive care needs compared to routine care, with assessments completed before and 4

Real-world data on HER2-positive metastatic CRC from 14 Japanese centers

Skip to content The CRC Digest ◇ RESEARCH Real-world data on HER2-positive metastatic CRC from 14 Japanese centers A multicenter retrospective study of 45 patients with HER2-positive metastatic colorectal cancer diagnosed between 2010 and 2023 examined outcomes with different first-line targeted agents and assessed safety of trastuzumab plus pertuzumab. (International Journal

American Cancer Society adds blood-based tests to CRC screening guidelines

Skip to content The CRC Digest ▪ SCREENING American Cancer Society adds blood-based tests to CRC screening guidelines In May 2026, the American Cancer Society updated their recommendations to include blood-based tests for individuals who decline or do not complete preferred screening tests, with a colonoscopy within 6 months required for

CRC Research Update — September 05, 2026

Today's colorectal cancer research highlights

Immune Recovery After Surgery Linked to ctDNA Minimal Residual Disease

Skip to content The CRC Digest Immune Recovery After Surgery Linked to ctDNA Minimal Residual Disease A prospective study of 1,000 stage II-III CRC patients found that distinct perioperative immunocircadian recovery trajectories were associated with postoperative ctDNA-based minimal residual disease and long-term survival outcomes. (Surgery) This content is informational

Biological Age and Neighborhood Deprivation Linked to Psychological Distress During Chemotherapy

Skip to content The CRC Digest ♥ LIVING WITH CRC Biological Age and Neighborhood Deprivation Linked to Psychological Distress During Chemotherapy An analysis of 958 adults with stage II-III CRC receiving chemotherapy found that biological age and neighborhood deprivation predict depression and anxiety symptoms, highlighting biosocial factors that may influence mental

Circulating Tumor DNA Predicts Recurrence After Liver Metastasis Resection

Skip to content The CRC Digest ◇ RESEARCH Circulating Tumor DNA Predicts Recurrence After Liver Metastasis Resection A systematic review and meta-analysis found that circulating tumor DNA (ctDNA) serves as a biomarker for recurrence after curative resection of colorectal cancer liver metastases, potentially guiding post-surgical surveillance strategies. (Clinical Colorectal Cancer) This

KRAS Mutation Enriches Gut Bacteria Linked to Tumor Growth

Skip to content The CRC Digest ◇ RESEARCH KRAS Mutation Enriches Gut Bacteria Linked to Tumor Growth A study in KRAS-mutant CRC patients and mice found that KRAS reshapes the microbial community, enriching Bacteroides acidifaciens, which predicts poor prognosis and promotes malignant phenotypes in KRAS-mutant tumors. (Cell Host & Microbe) This

Multigene Panel Testing Yield Quantified in Colorectal Cancer Patients

Skip to content The CRC Digest ◇ RESEARCH Multigene Panel Testing Yield Quantified in Colorectal Cancer Patients A systematic review and meta-analysis examined the diagnostic yield of germline multigene panel testing using next-generation sequencing in unselected patients with colorectal cancer, helping clarify how often inherited genetic factors contribute to diagnosis. (Lancet