Blood-based DNA methylation test shows promise for early detection Skip to content The CRC Digest Blood-based DNA methylation test shows promise for early detection A pilot study of 50 participants in Gaza evaluated circulating tumor DNA methylation biomarkers (SEPT9, SPG20, ALX4, MGMT, and RASSF1A) for non-invasive colorectal cancer detection, with multi-gene panels showing improved diagnostic performance. (Clinica Chimica Acta)
Prior anti-EGFR therapy affects HER2-targeted treatment outcomes Skip to content The CRC Digest ▸ TREATMENT Prior anti-EGFR therapy affects HER2-targeted treatment outcomes — ESMO Open An integrated analysis of the TRIUMPH and MyPathway studies examined how prior treatment with anti-EGFR (epidermal growth factor receptor) therapy affects the effectiveness of pertuzumab plus trastuzumab in HER2-amplified metastatic colorectal cancer. The study