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microbiome

A collection of 5 issues

Gut Microbiota Differs Between MSI-H and MSS Colorectal Cancer

Skip to content The CRC Digest Gut Microbiota Differs Between MSI-H and MSS Colorectal Cancer A study collected fecal samples from CRC patients with different microsatellite states and healthy individuals to explore differences in gut microbiota between MSI-H and MSS colorectal cancer, potentially providing new directions for immunotherapy in MSS

CRC Research Finding

Skip to content The CRC Digest ◇ Systematic review examines Fusobacterium nucleatum as predictor of treatment response A systematic review evaluated whether Fusobacterium nucleatum, a bacterium implicated in CRC progression and immune modulation, can predict treatment response, though its role as a biomarker remains unclear. (Cancer Treatment Reviews) This content is

Microbiota influences immunotherapy efficacy in MSI-H colorectal cancer

Skip to content The CRC Digest Microbiota influences immunotherapy efficacy in MSI-H colorectal cancer Immune checkpoint inhibitors benefit patients with mismatch repair-deficient/microsatellite instability-high colorectal cancer, and gut microbiota appears to play a key role in treatment response. (Life Sciences) This content is informational only and does not constitute medical

CRC Research Finding

Skip to content The CRC Digest ◇ Review highlights gut microbiota's role in immunotherapy response, especially for MSI-H tumors A comprehensive review evaluates how gut microbiota and microbial metabolites influence colorectal cancer development, the tumor microenvironment, and immunotherapy responses, with emphasis on strategies for proficient mismatch repair/microsatellite-stable tumors

Cross-kingdom gut microbiome model predicts colorectal adenomas

Skip to content The CRC Digest Cross-kingdom gut microbiome model predicts colorectal adenomas Researchers analyzed 296 fecal samples using metagenomic sequencing and developed a predictive model incorporating bacteria, viruses, archaea, and fungi to identify colorectal adenomas, the main precancerous lesion. (Front Microbiol) This content is informational only and does not